Elena Kaschina, Thomas Unger
Angiotensin II (Ang II), a major biologically active component of the renin-angiotensin system (RAS), acts through two receptor subtypes, the AT1 and the AT2 receptor. The AT1 receptor mediates the...
Hot Topics In Hypertension, Issue 14, 2012, ISSN 1973-963X
Kai Kappert, Thomas Unger
The renin-angiotensin system (RAS) plays a crucial role in the organized mechanisms that regulate both electrolyte/ blood volume homeostasis and blood pressure. In general, factors reducing blood...
Hot Topics In Hypertension, Issue 4, 2008, ISSN 1973-963X
Jan H. Schefe, Thomas Unger
The use of angiotensin AT1 receptor antagonists, or blockers (ARBs), is the most recent step toward innovating antihypertensive drugs in the past 50 years. The first compound of this new drug class,...
Hot Topics In Cardiology, Issue 5, 2007, ISSN 1973-9621